Presentation emphasising the significance of dermoscopy in diagnosing acquired palmar keratoderma. Palmar keratodermas are common reasons for dermatology consultations, with diverse etiologies ranging from inflammatory to infectious or mechanical causes. Dr. Rabhi highlighted that dermoscopy can serve as a quick and non-invasive diagnostic tool, avoiding the need for skin biopsies in certain cases. She discussed the dermoscopic analysis, focusing on color, vessels, and scales distribution. Using various case examples, she demonstrated how dermoscopy can help differentiate between conditions like psoriasis, eczema, lichen planus, pityriasis rubra pilaris, and others, providing valuable insights for accurate diagnosis and patient management.