Chormoblastomycosis and Rhinoentomophtoromycosis

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Chromoblastomycosis is a subcutaneous mycosis that affects the skin and subcutaneous tissue.
It is located preferentially in the lower extremities and is characterized by verrucous, nodular,
or atrophic lesions with a chronic evolution and difficult treatment. It originates from infection
with black fungi (dematiaceous or pheoid), mainly from the genera Fonsecaea sp., Phialophora
and Cladophialophora (Cladosporium carrionii), which in their parasitic form appear as
fumagoid cells. It predominates in rural areas, particularly in tropical and subtropical climates.
Conidiobolomycosis is also a subcutaneous mycosis, cause mainly by Conidiobolus coronatus
and it is characterized by rhinofacial edema and infiltration, usually affecting
immunocompetent hosts. The characteristic histopathologic finding is the “Splendore-Hoeppli
phenomenon,” which is an antigen– antibody reaction manifested by hyphae surrounded by an
eosinophilic halo. An etiological diagnosis is established by culture, but the fungus is rarely
isolated. Both entities are part of the Neglected Tropical Diseases, with a high cure rate if the
diagnosis is made on time and the proper treatment is given. Multiple therapeutic combination
area described, but the lack of access of heatlh care and expensive treatments make it difficult
to address these pathologies on time.
Keywords: rhinofacial, chromomycosis, subcutaneous mycosis.