Julio Cesar Salas-Alanis
POSITION TITLE: Dermatology Professor, Instituto Dermatologico de Jalisco, Mexico.
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and residency training if applicable. Add/delete rows as necessary.)
INSTITUTION AND LOCATIONDEGREE
Universidad Autonoma de Nuevo Leon, Mexico
Universidad de Barcelona Hospital Clinic I ProvincialDoc med12-2015
12-1993Genodermatosis
Instituto Dermatologico de Jalisco, Mexico
Instituto Dermatologico de Jalisco,Mexico
Universidad Autonoma de Nuevo Leon, Mexico
Dermatology
M.D.12-1992
12-1991
12-1987Dermatopathology
Dermatology
Medical Doctor
FIELD OF STUDY
Universidad Autonoma de Nuevo Leon, Mexico
Universidad de Barcelona Hospital Clinic I ProvincialDoc med12-2015
12-1993Genodermatosis
Instituto Dermatologico de Jalisco, Mexico
Instituto Dermatologico de Jalisco,Mexico
Universidad Autonoma de Nuevo Leon, Mexico
Dermatology
M.D.12-1992
12-1991
12-1987Dermatopathology
Dermatology
Medical Doctor
Personal Statement
Dermatologist from Mexico, researcher since 1995, member of Local and National Dermatology Societies. Member of the American Academy of Dermatology, and International Dermatology Society.
Founder of Dystrophic Epidermolysis Bullosa Research Association Mexico (1995) DEBRA MEXICO AC.
He is one of the Genodermatosis researcher leaders in Mexico and Latin-American, after one year spent at the Universidad Autonoma de Barcelona (Hospital Clinic I Provincial) Spain, learning Dermatopathology he moved to learn Immunofluorescence techniques for the Diagnosis of Immunoblistering and Autoimmune disorders at St. Johns Institute of London in the Kings College London.
In Mexico,1994 he founded The Dystrophic Epidermolysis Bullous Research Association Mexico (DebRA Mexico), a nonprofit association to give support to the patients with a rare genetic disease; Epidermolysis Bullosa.
More than 300 hundred papers have published, 102 on pubmed; Science Translational Medicine, Oncotarget, Nature Communications, American Journal of Dermatology, Journal of Investigative in Dermatology, American Human Genetics, PLOS, PNAS, and some others.
Local and National awards on the Research field as the National Prize for his volunteer job as Founder and President of DebRA MEXICO, (Dystrophic Epidermolysis Bullous Research Association)
Community leadership skinpactGalderma award 2016 for the Association DEBRA MEXICO.
International Collaborations with different Universities in USA: Columbia, Angela Christiano (Genotrichosis, Epidermolysis Bullosa, Trichothiodystrophy), Thomas Jefferson, Jouni Uitto, Andy South, (Epidermolysis Bullosa, microbiota, squamous cell carcinoma,), Stanford, Peter Marinkovici (Epidermolysis Bullosa), Yale, Keith Choate (Hypohidrotic Ectodermal Dysplasias), London, John McGrath (Genodermatosis), Sydney, Dedee Murrel and some others.
Dr. Salas-Alanis is well known dermatologist in Mexico, Latino America and some countries around the world for his enthusiasm, energy and easy way to see the social problems.
His empathy to others has been a reason for his success on life.
Positions and Honors
Professor and Researcher Univirsidad Autonoma de Mexico and Instituto Dermatologico de Jalisco, Mexico.
Visiting Professor at Dermatology Dept of Yale University, New Haven Connecticut 2013-2014
Professor & Researcher School of Medicine Universidad de Monterrey 2013-2018
Professor & Researcher Dermatology Dept, Hospital Universitario, Monterrey Nuevo Leon 2009-2013
Professor & Researcher School of Medicine, Instituto de Estudios Superiores del Tecnolgico de Monterrey 2004-2013
Director of Dermatology Services, Servicios Mdicos de la Universidad Autnoma de Nuevo Leon 1994-2007.
Dermatology Adjunct Professor School of Medicine, Universidad de Monterrey 2002-2004
Professor of Histology Medicine School Universidad Autonoma de Nuevo Leon 1993-1997.
Contributions to Science
As a founder of Dystrophic epidermolysis Bullosa Research Association in Mexico (DebRA) his main field of work has been EB. His work on EB, started in 1994 with the first publications reporting this disease in Latin America, his collaborations have demonstrated how some patients present a phenotype that is opposite to the genotype of the mutation. He has studied a group of EB patients that have survived for over 60 years with an aggressive disease variant without suffering from squamous cell carcinoma. In collaboration with Dr. Angela Christiano, they worked on a study utilizing CRISPR Cas-9 techniques to produce 3D models of skin with the idea of grafting the wounds of EB patients.
In the year 2012, he published on the JAAD joural, with international collaboration the second scoring system in the history of this disease: the Epidermolysis Bullosa Oropharyngeal Severity (EBOS) score: a multicenter development and reliability assessment. This score attempts to evaluate the severity of EB in the oropharyngeal cavity, which is many times is forgotten upon physical examination of these patients.
For the last 20 years, his collaboration with Andrew South in molecular research for Squamous Cell Carcinoma that affects these patients has allowed for a deeper understanding regarding the aggressiveness of this often-fatal cancer.
As a part of DebRA International and his interest in collaborating to improve patients quality of life he has published in 2016 at the BJD, The Management of cutaneous squamous cell carcinoma in patients with epidermolysis bullosa: best clinical practice guidelines.
In the year 2021, he published in J Rare Dis; Physiotherapy for epidermolysis bullosa: clinical practice guidelines.
He has contributed in a multitude of studies for mutations such as Hypohidrotic EctodermalDysplasia, GAPO Syndrome, Olmsted, palmoplantar keratoderma punctata, Pseudoxanthoma elasticum and other genetic diseases.
His last contribution is proposing haematohidrosis and haematolacria as a possible genetic disease by realizing the first exome sequencing study, finding genes related to the extracellular matrix as a possible cause. He was also the first to use the term trichorrage by demostrating how the erythrocytes exit through the pillous folilicle..
Additional Information: Research Support and/or Scholastic Performance
As a research Support professor he has been collaborating with several protocols of different groups around the world.
Research Professor of Dermatology, Instituto Dermatologico de Jalisco and Universidad Autonoma de Mexico 2017-2021.
Research Professor of Dermatology. Escuela de Medicina, Universidad de Monterrey. N.L. Mxico, Agosto 2012-2017.
Visiting Dermatologist, Universidad de Yale, New Haven Connecticut USA, 2013-2014.
Research Professor of Dermatology, Dermatologa del Hospital Universitario de la Universidad Autnoma de Nuevo Leon, 2010-2013.
Research Professor of Dermatology Escuela de Medicina del Instituto Teconolgico de Estudios Superiores Monterrey N.L. 2004-2013.
Chief of Dermatology Services Servicos Mdicos de la Universidad Autnoma de Nuevo Lon, 1994-2007.
Dermatology Professor Universidad de Monterrey, 2002-2006.
Histology Professor Facultad de Medicina de la UANL, 993-1997.