Blaschko lines are a distribution of skin lines which can be found in certain dermatosis, often genetic.
Examples include incontinentia pigmenti, epidermal nevus, lichen striatus…
These lines carry the name of Dr Alfred Blaschko (1858-1922), a German dermatologist who described the lines on a statue and published the pictoral diagram in 1901.
The cause of the lines is unknown, but one hypothesis is that they are the result of lyonization, X-inactivation which is a process by which one of the two copies of the X chromosome present in females (XX) is inactivated.
Source of information: Crissey JT el al. Dermatology and Dermatologists (2002). Parthenon Publishing
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