Relapse factors of pemphigus: a comparative study of 219 cases.

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Pemphigus is a chronic autoimmune disease caused by humoral response withmediated autoantibodiesdirected against desmogleinproteins. The aim of our studywastoidentifyfactorsassociatedwithclinicalrelapseinMoroccanpemphiguspatients. In our study, we demonstrated new factors associated with a great risk of relapse such as the pemphigus herpetiformis subtype,the non association with the IFI rate, koebner phenomenon… We believe that our study brings new informations to dermatologist, internists and general practionnersin order to help clinicians to anticipate the relapses.